Janine Fredericks-Younger

Dr. Fredericks-Younger is the Chief Clinical Officer in the Opioid Analgesic Reduction Study (OARS), an NIH-funded clinical trial led by PI, Dr. Cecile Feldman. OARS is a double-blind, prospective, stratified, randomized clinical trial investigating post-operative analgesia using the impacted 3rd molar extraction pain model. She was also a co-investigator for the Pragmatic Return to Effective Dental Infection Control through Triage and Testing (PREDICT) study, an XO1 grant funded by NIH. This feasibility study examined the implementation of COVID-related testing and triage procedures in private dental offices as it relates to the safety and perception of the safety of DHCWs and patients. In addition to her research endeavors, she has served in various administrative capacities throughout her tenure at RSDM. Currently, she serves as the Associate Dean for Graduate Programs, responsible for overseeing the Dental School’s postgraduate academic enterprise, including all advanced education programs and master’s programs. She is an active member of various RSDM committees, serving as chair for the Planning Committee and the Vendor Committee.

B.A., The Johns Hopkins University, Baltimore, MD

D.M.D., Tufts University School of Dental Medicine, Boston, MA      

Certificate, General Practice Residency, Tufts University School of Dental Medicine, Boston, MA

Acute Dental Pain

1.  Feldman CA, Fredericks-Younger J, Desjardins PJ, Malmstrom H, Miloro M, Warburton G, Ward B, Ziccardi V, Fine DH, Greenberg P, Andrews T, Matheson PB, Lu SE. The Opioid Analgesic Reduction Study (OARS) Pilot: A Double-Blind Randomized Multicenter Trial. JDR Clin Trans Res. 2024 Jan;9(1):72-84. doi: 10.1177/23800844221144031. Epub 2023 Jan 20. PMID: 36680313; PMCID: PMC10850879.
2. Feldman CA, Fredericks-Younger J, Lu SE, et al. The Opioid Analgesic Reduction Study (OARS)-a comparison of opioid vs. non-opioid combination analgesics for management of post-surgical pain: a double-blind randomized clinical trial. Trials. 2022;23(1):160. Published 2022 Feb 17. doi:10.1186/s13063-022-06064-8
3. Fredericks-Younger, Feldman, Lu, Desjardins, Malstrom, Miloro, Warburton, Ward, Ziccardi, Fine, Andrews, Greenberg, Matheson; Opioids’ Impact on Pain-Interference and Sleep: The OARS Pilot Study; Presented at the International Association for Dental Research (IADR) Annual Session, 6/2022. https://iadr.abstractarchives.com/abstract/22iags-3722740/opioids-impact-on-pain-interference-and-sleep-the-oars-pilot-study
4. Fredericks-Younger J, Greenberg P, Andrews T, Matheson P, Lu S. Feldman-Zohn CA; Using REDCap to Enhance Data Quality in Clinical Trials; Presented at the American Association for Dental, Oral, and Craniofacial Research (AADOCR) Annual Session, 3/2022. https://iadr.abstractarchives.com/abstract/51am-3664582/using-redcap-to-enhance-data-quality-in-clinical-trials.

COVID-19 and Practice-based Research

1. Fredericks-Younger J, Fine DH, Subramanian G, Coker MO, Meyerowitz C, Ragusa P, Allareddy V, McBurnie MA, Funkhouser E, Gennaro ML, Feldman CA. The Pragmatic Return to Effective Dental Infection Control through Triage and Testing (PREDICT): Protocol for a Prospective Clinical Study in the National Dental Practice-Based Research Network. JMIR Research Protocols. 06/08/2022:38386
2. Feldman CA, Fredericks-Younger J, Subramanian G, Gennaro ML, Coker MO, Fine DH. Severe acute respiratory syndrome coronavirus 2 screening to augment dental office and patient safety [published online ahead of print, 2022 Jan 24]. J Am Dent Assoc. 2022; S0002-8177(22)00031-9. doi: 10.1016/j.adaj.2021.12.011
3. Coker MO, Subramanian G, Davidow A, Fredericks-Younger J, Gennaro m, Fine, DH, Feldman CA. Impact of DHCWs' Safety Perception on Vaccine Acceptance and Adoption of Risk Mitigation Strategies [published online ahead of print, 2022 Feb 22]. JDR Clin Trans Res. 2022;23800844211071111. doi:10.1177/23800844211071111

A completed list of published work can be found in Pubmed here.